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MECHANOSENSITIVE BRAIN TUMOR CELLS CONSTRUCT BLOOD-TUMOR BARRIER TO MASK CHEMOSENSITIVITY
Introduction: Brain cancer treatment is notoriously difficult due to the blood-tumor barrier (BTB) that restricts the penetration of...

Syed Rob
Aug 31, 20243 min read
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DECODING AUTISM: THE ROLE OF CEREBELLAR CONNECTIONS AND GENETIC MUTATIONS IN SOCIAL BEHAVIOR
Introduction: Over the past few decades, the relevance of the cerebellar connectome is emerging. The cerebellum is heavily connected...

Aditya Srinivasan
Jul 28, 20242 min read
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MIR-222 REGULATES THE PROGRESSION OF ORAL SQUAMOUS CELL CARCINOMA BY TARGETING CDKN1B
Introduction: Oral squamous cell carcinoma (OSCC) is a prevalent and aggressive form of cancer affecting the oral cavity, with...

Daniel Crestwell
Aug 17, 20233 min read
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THE FIRST ALCOHOL DRINK TRIGGERS MTORC1-DEPENDENT SYNAPTIC PLASTICITY IN NUCLEUS ACCUMBENS DOPAMINE D1 RECEPTOR NEURONS
Introduction: Early binge-like alcohol drinking may promote the development of hazardous intake. However, the enduring cellular...

Liam Norwood
Aug 10, 20233 min read
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ROLE OF MTOR-REGULATED AUTOPHAGY IN SPINE PRUNING DEFECTS AND MEMORY IMPAIRMENTS INDUCED BY BINGE-LIKE ETHANOL TREATMENT IN ADOLESCENT MICE
Introduction: Adolescence is a critical period for brain maturation, characterized by significant remodeling and changes in synaptic...

Kiara Hawthorne
Aug 3, 20232 min read
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P53 UPREGULATED MODULATOR OF APOPTOSIS SENSITIZES DRUG-RESISTANT U251 GLIOBLASTOMA STEM CELLS TO TEMOZOLOMIDE THROUGH ENHANCED APOPTOSIS
Introduction: Malignant glioma is a highly aggressive brain tumor with a dismal prognosis. Temozolomide (TMZ), a DNA-alkylating agent,...

Aanya Malhotra
Jul 20, 20234 min read
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ACTIVATION OF THE JAK/STAT3 PATHWAY IN ASTROCYTES IN ALZHEIMER'S AND HUNTINGTON'S DISEASE
Introduction: Astrocyte reactivity, characterized by molecular, morphological, and functional changes, is a hallmark of...

Adeline Vandermeer
Jul 13, 20233 min read
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NEURO-MECHANICS OF RECUMBENT LEG CYCLING IN POST-ACUTE STROKE PATIENTS
Introduction: Cycling training is widely used in post-stroke rehabilitation to improve motor function and aerobic capacity. However, the...

Alisha Chandran
Jul 6, 20233 min read
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TRANSFECTION OF BRAIN CAPILLARY ENDOTHELIAL CELLS IN PRIMARY CULTURE WITH DEFINED BLOOD–BRAIN BARRIER PROPERTIES
Introduction: The blood-brain barrier (BBB) is crucial for maintaining the central nervous system's (CNS) environment, formed by...

Syed Rob
Jun 29, 20233 min read
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A BIDIRECTIONAL ASSOCIATION BETWEEN THE GUT MICROBIOTA AND CNS DISEASE IN A BIPHASIC MURINE MODEL OF MULTIPLE SCLEROSIS
Introduction: Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system (CNS), leading to...

Oliver Keswick
Jun 22, 20233 min read
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THE LINK BETWEEN ANXIETY AND TESTOSTERONE
Introduction: Anxiety disorders can significantly impact daily life, and recent groundbreaking research led by Prof. Shira Knafo at...

Sophia Manfred
Jun 15, 20232 min read
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